BRD-K34294489_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

77 genes differentially expressed following the BRD-K34294489_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CD24 CD24 molecule
CD9 CD9 molecule
CDC25B cell division cycle 25B
CFD complement factor D (adipsin)
CLDN10 claudin 10
CPVL carboxypeptidase, vitellogenic-like
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP2 cysteine and glycine-rich protein 2
CYTH1 cytohesin 1
DEFB1 defensin, beta 1
DUSP6 dual specificity phosphatase 6
F13A1 coagulation factor XIII, A1 polypeptide
FBLN1 fibulin 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
FZD7 frizzled class receptor 7
GPX3 glutathione peroxidase 3
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1R2 interleukin 1 receptor, type II
IRS2 insulin receptor substrate 2
JAG1 jagged 1
KIF5C kinesin family member 5C
KYNU kynureninase
LEFTY1 left-right determination factor 1
LRRC16A leucine rich repeat containing 16A
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTSS1 metastasis suppressor 1
NMU neuromedin U
PPAP2B phosphatidic acid phosphatase type 2B
PTX3 pentraxin 3, long
RAP1GAP RAP1 GTPase activating protein
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SORBS3 sorbin and SH3 domain containing 3
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMC5 transmembrane channel-like 5
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSKU tsukushi, small leucine rich proteoglycan
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
C2CD5 C2 calcium-dependent domain containing 5
CCND2 cyclin D2
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COL4A5 collagen, type IV, alpha 5
CXCL13 chemokine (C-X-C motif) ligand 13
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGF13 fibroblast growth factor 13
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HOXC6 homeobox C6
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LYZ lysozyme
MGP matrix Gla protein
NPY1R neuropeptide Y receptor Y1
PLK1 polo-like kinase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TXNIP thioredoxin interacting protein
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A