BRD-K33882852_ZK 93423_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K33882852_ZK 93423_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
ECM1 extracellular matrix protein 1
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
HILPDA hypoxia inducible lipid droplet-associated
IDS iduronate 2-sulfatase
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
KRT17 keratin 17, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MN1 meningioma (disrupted in balanced translocation) 1
NDRG1 N-myc downstream regulated 1
NRN1 neuritin 1
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PSD3 pleckstrin and Sec7 domain containing 3
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RPS11 ribosomal protein S11
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPAG4 sperm associated antigen 4
STK17A serine/threonine kinase 17a
SYNM synemin, intermediate filament protein
TPD52L1 tumor protein D52-like 1
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MXRA5 matrix-remodelling associated 5
OAT ornithine aminotransferase
PEG3 paternally expressed 3
SPON1 spondin 1, extracellular matrix protein
TCF4 transcription factor 4