BRD-K33860217_CP 94253 hydrochloride_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K33860217_CP 94253 hydrochloride_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
CCND2 cyclin D2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSTA cystatin A (stefin A)
EPCAM epithelial cell adhesion molecule
HOXC10 homeobox C10
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ITGA6 integrin, alpha 6
LTF lactotransferrin
LXN latexin
MUC1 mucin 1, cell surface associated
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
PDZD8 PDZ domain containing 8
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTK2 protein tyrosine kinase 2
QPCT glutaminyl-peptide cyclotransferase
SELL selectin L
SERINC5 serine incorporator 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SRSF6 serine/arginine-rich splicing factor 6
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYT1 synaptotagmin I
TBC1D4 TBC1 domain family, member 4
TSPAN13 tetraspanin 13
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ANXA3 annexin A3
ANXA5 annexin A5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
DACH1 dachshund family transcription factor 1
DDR2 discoidin domain receptor tyrosine kinase 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLC1 DLC1 Rho GTPase activating protein
EFNB2 ephrin-B2
GPATCH8 G patch domain containing 8
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IL32 interleukin 32
LRRC17 leucine rich repeat containing 17
MSLN mesothelin
MYRF myelin regulatory factor
PCNA proliferating cell nuclear antigen
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLLP plasmolipin
PNMA2 paraneoplastic Ma antigen 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN2 reticulon 2
SIRT3 sirtuin 3
SLC38A1 solute carrier family 38, member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNX7 sorting nexin 7
SST somatostatin
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TGFB3 transforming growth factor, beta 3
TIMP2 TIMP metallopeptidase inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
TOX thymocyte selection-associated high mobility group box
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
TYRP1 tyrosinase-related protein 1
VCAM1 vascular cell adhesion molecule 1