BRD-K33379087_tivantinib_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K33379087_tivantinib_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL2 chemokine (C-C motif) ligand 2
CD44 CD44 molecule (Indian blood group)
DRAM1 DNA-damage regulated autophagy modulator 1
EXT1 exostosin glycosyltransferase 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HIST1H2BD histone cluster 1, H2bd
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
ISOC1 isochorismatase domain containing 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing

decreased expression

Symbol Name
AGR2 anterior gradient 2
BRCA1 breast cancer 1, early onset
FBP1 fructose-1,6-bisphosphatase 1
LAMP5 lysosomal-associated membrane protein family, member 5
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LXN latexin
NRGN neurogranin (protein kinase C substrate, RC3)
PSPH phosphoserine phosphatase
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C
VAV3 vav 3 guanine nucleotide exchange factor