BRD-K33272502_DG-041_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K33272502_DG-041_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
BBX bobby sox homolog (Drosophila)
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC11A C-type lectin domain family 11, member A
COL4A5 collagen, type IV, alpha 5
CPB1 carboxypeptidase B1 (tissue)
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EIF5A eukaryotic translation initiation factor 5A
FGF13 fibroblast growth factor 13
GARS glycyl-tRNA synthetase
GRB7 growth factor receptor-bound protein 7
GSE1 Gse1 coiled-coil protein
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIAA1033 KIAA1033
KRAS Kirsten rat sarcoma viral oncogene homolog
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MDFIC MyoD family inhibitor domain containing
NBPF10 neuroblastoma breakpoint family, member 10
OAT ornithine aminotransferase
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PLAGL1 pleiomorphic adenoma gene-like 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAP2A RAP2A, member of RAS oncogene family
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRRM2 serine/arginine repetitive matrix 2
TFPI2 tissue factor pathway inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNNT1 troponin T type 1 (skeletal, slow)
TPSAB1 tryptase alpha/beta 1
TRPS1 trichorhinophalangeal syndrome I
UGCG UDP-glucose ceramide glucosyltransferase
VEGFA vascular endothelial growth factor A
WSB1 WD repeat and SOCS box containing 1
XBP1 X-box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCDC85B coiled-coil domain containing 85B
CCDC86 coiled-coil domain containing 86
CCL5 chemokine (C-C motif) ligand 5
CCNE2 cyclin E2
CD59 CD59 molecule, complement regulatory protein
CLU clusterin
CSRP1 cysteine and glycine-rich protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FEN1 flap structure-specific endonuclease 1
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
GNAS GNAS complex locus
IFITM1 interferon induced transmembrane protein 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAT2A methionine adenosyltransferase II, alpha
MMP7 matrix metallopeptidase 7
MT1X metallothionein 1X
MYH11 myosin, heavy chain 11, smooth muscle
NOP16 NOP16 nucleolar protein
PPIF peptidylprolyl isomerase F
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRPF19 pre-mRNA processing factor 19
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SLPI secretory leukocyte peptidase inhibitor
SRSF7 serine/arginine-rich splicing factor 7
TSPAN8 tetraspanin 8
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1