BRD-K33272502_DG-041_RMUGS_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K33272502_DG-041_RMUGS_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZIN1 antizyme inhibitor 1
BTG3 BTG family, member 3
CD200 CD200 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL15A1 collagen, type XV, alpha 1
CPE carboxypeptidase E
DDIT4 DNA-damage-inducible transcript 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOK5 docking protein 5
FBLN1 fibulin 1
FGG fibrinogen gamma chain
FLRT2 fibronectin leucine rich transmembrane protein 2
FOLR1 folate receptor 1 (adult)
GATA6 GATA binding protein 6
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HIST1H2AC histone cluster 1, H2ac
HOXB6 homeobox B6
KCTD12 potassium channel tetramerization domain containing 12
LGALS2 lectin, galactoside-binding, soluble, 2
LMO4 LIM domain only 4
LOC100505650 uncharacterized LOC100505650
MEF2C myocyte enhancer factor 2C
MYH10 myosin, heavy chain 10, non-muscle
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PLS3 plastin 3
PLXNC1 plexin C1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SARS seryl-tRNA synthetase
SCGB1D2 secretoglobin, family 1D, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SNX13 sorting nexin 13
SPON2 spondin 2, extracellular matrix protein
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ADIRF adipogenesis regulatory factor
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC11A C-type lectin domain family 11, member A
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GOLGA4 golgin A4
GPX2 glutathione peroxidase 2
GSN gelsolin
HOXC10 homeobox C10
IGL immunoglobulin lambda locus
ITGB4 integrin, beta 4
KIAA0485 uncharacterized LOC57235
KLF11 Kruppel-like factor 11
LPL lipoprotein lipase
MAOB monoamine oxidase B
MXRA7 matrix-remodelling associated 7
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM4 olfactomedin 4
OSBPL8 oxysterol binding protein-like 8
PKM pyruvate kinase, muscle
PRKCA protein kinase C, alpha
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORBS3 sorbin and SH3 domain containing 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYNM synemin, intermediate filament protein
TAC1 tachykinin, precursor 1
TMEM255A transmembrane protein 255A
TRAK1 trafficking protein, kinesin binding 1
TSPYL5 TSPY-like 5
TXLNA taxilin alpha
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)