BRD-K33272502_DG-041_PC3_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

106 genes differentially expressed following the BRD-K33272502_DG-041_PC3_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
CARS cysteinyl-tRNA synthetase
CCBL2 cysteine conjugate-beta lyase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN3 claudin 3
CLIC4 chloride intracellular channel 4
CTH cystathionine gamma-lyase
CXCL3 chemokine (C-X-C motif) ligand 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EPRS glutamyl-prolyl-tRNA synthetase
FKBP11 FK506 binding protein 11, 19 kDa
FOXO1 forkhead box O1
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GRIA2 glutamate receptor, ionotropic, AMPA 2
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOMER2 homer scaffolding protein 2
HSPA13 heat shock protein 70kDa family, member 13
IARS isoleucyl-tRNA synthetase
IFRD1 interferon-related developmental regulator 1
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
JUND jun D proto-oncogene
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MARS methionyl-tRNA synthetase
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RSL24D1 ribosomal L24 domain containing 1
S100P S100 calcium binding protein P
SARS seryl-tRNA synthetase
SERP1 stress-associated endoplasmic reticulum protein 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOD2 superoxide dismutase 2, mitochondrial
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STC2 stanniocalcin 2
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIB3 tribbles pseudokinase 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AQP3 aquaporin 3 (Gill blood group)
B3GNT1
CAV1 caveolin 1, caveolae protein, 22kDa
CDCA4 cell division cycle associated 4
CFD complement factor D (adipsin)
CSRP1 cysteine and glycine-rich protein 1
CXADR coxsackie virus and adenovirus receptor
DPYSL3 dihydropyrimidinase-like 3
DUSP4 dual specificity phosphatase 4
EFNB2 ephrin-B2
ENO1 enolase 1, (alpha)
F2R coagulation factor II (thrombin) receptor
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BD histone cluster 1, H2bd
HOXA10 homeobox A10
HOXB7 homeobox B7
KRT1 keratin 1, type II
KRT18 keratin 18, type I
KRT7 keratin 7, type II
MID1 midline 1
NFIB nuclear factor I/B
NMU neuromedin U
NREP neuronal regeneration related protein
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
SDC1 syndecan 1
SFN stratifin
SPON1 spondin 1, extracellular matrix protein
SYNM synemin, intermediate filament protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
WWTR1 WW domain containing transcription regulator 1