BRD-K33272502_DG-041_LOVO_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

139 genes differentially expressed following the BRD-K33272502_DG-041_LOVO_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADD3 adducin 3 (gamma)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
ANXA4 annexin A4
ANXA9 annexin A9
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BGN biglycan
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CLIC4 chloride intracellular channel 4
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL3 dihydropyrimidinase-like 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ESRP1 epithelial splicing regulatory protein 1
FAM129A family with sequence similarity 129, member A
FHL2 four and a half LIM domains 2
FTH1 ferritin, heavy polypeptide 1
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GSTM3 glutathione S-transferase mu 3 (brain)
H1F0 H1 histone family, member 0
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
KLK5 kallikrein-related peptidase 5
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LCN2 lipocalin 2
LRP2 low density lipoprotein receptor-related protein 2
MAP7 microtubule-associated protein 7
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MYB v-myb avian myeloblastosis viral oncogene homolog
OBSL1 obscurin-like 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHYH phytanoyl-CoA 2-hydroxylase
PPIF peptidylprolyl isomerase F
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PXDN peroxidasin
QPRT quinolinate phosphoribosyltransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RDX radixin
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A1 solute carrier family 38, member 1
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
THBS2 thrombospondin 2
VCAN versican
VGLL1 vestigial-like family member 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADRB2 adrenoceptor beta 2, surface
AKAP12 A kinase (PRKA) anchor protein 12
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CCNB2 cyclin B2
CCR1 chemokine (C-C motif) receptor 1
CD320 CD320 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD96 CD96 molecule
COLEC12 collectin sub-family member 12
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
EDNRB endothelin receptor type B
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM13A family with sequence similarity 13, member A
FASTKD5 FAST kinase domains 5
FKBP11 FK506 binding protein 11, 19 kDa
GJA1 gap junction protein, alpha 1, 43kDa
GPC4 glypican 4
HMG20B high mobility group 20B
LPL lipoprotein lipase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K2 mitogen-activated protein kinase kinase 2
MCTP1 multiple C2 domains, transmembrane 1
MFSD12 major facilitator superfamily domain containing 12
MPPED2 metallophosphoesterase domain containing 2
MRPS2 mitochondrial ribosomal protein S2
NTS neurotensin
PDE4D phosphodiesterase 4D, cAMP-specific
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLIN3 perilipin 3
POSTN periostin, osteoblast specific factor
PRUNE2 prune homolog 2 (Drosophila)
PTCH1 patched 1
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
REG3A regenerating islet-derived 3 alpha
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
SFTPA2 surfactant protein A2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX10 sorting nexin 10
SOAT1 sterol O-acyltransferase 1
SORBS1 sorbin and SH3 domain containing 1
STAG2 stromal antigen 2
TKTL1 transketolase-like 1
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPI1 triosephosphate isomerase 1
TRBC1 T cell receptor beta constant 1
TSPO translocator protein (18kDa)
TYMP thymidine phosphorylase
WIF1 WNT inhibitory factor 1