BRD-K33272502_DG-041_HT29_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K33272502_DG-041_HT29_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADM adrenomedullin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BTG1 B-cell translocation gene 1, anti-proliferative
CA1 carbonic anhydrase I
CARS cysteinyl-tRNA synthetase
CD24 CD24 molecule
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CLIC4 chloride intracellular channel 4
COL9A3 collagen, type IX, alpha 3
CRYAB crystallin, alpha B
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
FHL2 four and a half LIM domains 2
FLNB filamin B, beta
FOXO3 forkhead box O3
GARS glycyl-tRNA synthetase
H1F0 H1 histone family, member 0
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
IARS isoleucyl-tRNA synthetase
IER3 immediate early response 3
IFRD1 interferon-related developmental regulator 1
IGHM immunoglobulin heavy constant mu
IL6ST interleukin 6 signal transducer
JUN jun proto-oncogene
LINC00341 long intergenic non-protein coding RNA 341
MAP1B microtubule-associated protein 1B
MARS methionyl-tRNA synthetase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
RHOQ ras homolog family member Q
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100P S100 calcium binding protein P
SELL selectin L
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC38A1 solute carrier family 38, member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TARS threonyl-tRNA synthetase
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
XBP1 X-box binding protein 1
XPOT exportin, tRNA

decreased expression

Symbol Name
ANOS1 anosmin 1
ATF5 activating transcription factor 5
BCHE butyrylcholinesterase
CPB1 carboxypeptidase B1 (tissue)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FGF9 fibroblast growth factor 9
MEIS2 Meis homeobox 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
POLR1D polymerase (RNA) I polypeptide D, 16kDa
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN12 tetraspanin 12
TYRP1 tyrosinase-related protein 1
WIF1 WNT inhibitory factor 1