BRD-K33272502_DG-041_HCC515_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

80 genes differentially expressed following the BRD-K33272502_DG-041_HCC515_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
CARS cysteinyl-tRNA synthetase
CCL20 chemokine (C-C motif) ligand 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN4 claudin 4
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUOX2 dual oxidase 2
EGR1 early growth response 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
LGALS2 lectin, galactoside-binding, soluble, 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MET MET proto-oncogene, receptor tyrosine kinase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAT1 phosphoserine aminotransferase 1
SARS seryl-tRNA synthetase
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TFF1 trefoil factor 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
VNN1 vanin 1
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1
XPOT exportin, tRNA

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANXA4 annexin A4
BCHE butyrylcholinesterase
C3 complement component 3
CCND1 cyclin D1
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CP ceruloplasmin (ferroxidase)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRISP3 cysteine-rich secretory protein 3
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FRZB frizzled-related protein
GPNMB glycoprotein (transmembrane) nmb
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
IFI6 interferon, alpha-inducible protein 6
IL1R1 interleukin 1 receptor, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MCOLN1 mucolipin 1
MX1 MX dynamin-like GTPase 1
NLRP2 NLR family, pyrin domain containing 2
NOTCH1 notch 1
RBP1 retinol binding protein 1, cellular
SFN stratifin
SOX4 SRY (sex determining region Y)-box 4
TIMP3 TIMP metallopeptidase inhibitor 3
ZNF423 zinc finger protein 423