BRD-K32644160_Naphthalen-1-yl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K32644160_Naphthalen-1-yl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AMACR alpha-methylacyl-CoA racemase
C1QB complement component 1, q subcomponent, B chain
CHRDL1 chordin-like 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CPM carboxypeptidase M
ECI1 enoyl-CoA delta isomerase 1
EFNB2 ephrin-B2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAT1 histone acetyltransferase 1
HBD hemoglobin, delta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGFBP6 insulin-like growth factor binding protein 6
JAG1 jagged 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEIS2 Meis homeobox 2
MFAP5 microfibrillar associated protein 5
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
OSBPL10 oxysterol binding protein-like 10
PLN phospholamban
SCGB1D2 secretoglobin, family 1D, member 2
SORBS2 sorbin and SH3 domain containing 2
STC1 stanniocalcin 1
STK26 serine/threonine protein kinase 26
STS steroid sulfatase (microsomal), isozyme S
TCTA T-cell leukemia translocation altered
TEK TEK tyrosine kinase, endothelial
TMEM176B transmembrane protein 176B
TMSB15A thymosin beta 15a
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOX3 TOX high mobility group box family member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANXA6 annexin A6
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L2 chitinase 3-like 2
COL3A1 collagen, type III, alpha 1
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEFB1 defensin, beta 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GPRC5A G protein-coupled receptor, class C, group 5, member A
HOXC10 homeobox C10
HOXC6 homeobox C6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KLK11 kallikrein-related peptidase 11
KRT4 keratin 4, type II
LOX lysyl oxidase
MAB21L2 mab-21-like 2 (C. elegans)
MOXD1 monooxygenase, DBH-like 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
OXTR oxytocin receptor
PLK1 polo-like kinase 1
PRR4 proline rich 4 (lacrimal)
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELL selectin L
SRSF6 serine/arginine-rich splicing factor 6
TPD52 tumor protein D52
TSPAN3 tetraspanin 3