BRD-K32485462_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K32485462_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACKR3 atypical chemokine receptor 3
ACSL3 acyl-CoA synthetase long-chain family member 3
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BIRC3 baculoviral IAP repeat containing 3
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
EIF5A eukaryotic translation initiation factor 5A
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PTHLH parathyroid hormone-like hormone
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SQLE squalene epoxidase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
CD320 CD320 molecule
HOXC10 homeobox C10
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)