BRD-K30849099_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K30849099_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP11B ATPase, class VI, type 11B
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CD24 CD24 molecule
CDC25B cell division cycle 25B
CDCA8 cell division cycle associated 8
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CGA glycoprotein hormones, alpha polypeptide
CIT citron rho-interacting serine/threonine kinase
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK1 delta-like 1 homolog (Drosophila)
FGFR3 fibroblast growth factor receptor 3
HMG20B high mobility group 20B
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KRT17 keratin 17, type I
LDOC1 leucine zipper, down-regulated in cancer 1
LMNB2 lamin B2
LMO4 LIM domain only 4
MEF2C myocyte enhancer factor 2C
MKI67 marker of proliferation Ki-67
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEB nebulin
NEK2 NIMA-related kinase 2
NTS neurotensin
PHACTR2 phosphatase and actin regulator 2
PLK1 polo-like kinase 1
PLS3 plastin 3
PROM1 prominin 1
QKI QKI, KH domain containing, RNA binding
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TPX2 TPX2, microtubule-associated
TTK TTK protein kinase
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AHCY adenosylhomocysteinase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA2 annexin A2
BIK BCL2-interacting killer (apoptosis-inducing)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK6 cyclin-dependent kinase 6
CFI complement factor I
CTGF connective tissue growth factor
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
F12 coagulation factor XII (Hageman factor)
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KDM5D lysine (K)-specific demethylase 5D
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
NET1 neuroepithelial cell transforming 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PRR7 proline rich 7 (synaptic)
RAP1GAP RAP1 GTPase activating protein
RGS10 regulator of G-protein signaling 10
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORD sorbitol dehydrogenase
SPDEF SAM pointed domain containing ETS transcription factor
SYBU syntabulin (syntaxin-interacting)
TFRC transferrin receptor
TSPAN7 tetraspanin 7