BRD-K30849099_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K30849099_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASS1 argininosuccinate synthase 1
CAMP cathelicidin antimicrobial peptide
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL10A1 collagen, type X, alpha 1
COL8A2 collagen, type VIII, alpha 2
COMP cartilage oligomeric matrix protein
GAS6 growth arrest-specific 6
GPX1 glutathione peroxidase 1
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
IL17RB interleukin 17 receptor B
MT1F metallothionein 1F
ORM1 orosomucoid 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
SULF1 sulfatase 1
SUSD4 sushi domain containing 4
TCEAL2 transcription elongation factor A (SII)-like 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
C8ORF4 chromosome 8 open reading frame 4
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD81 CD81 molecule
CD99 CD99 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CST1 cystatin SN
CTSC cathepsin C
CTSH cathepsin H
DLC1 DLC1 Rho GTPase activating protein
EGFR epidermal growth factor receptor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
GDF15 growth differentiation factor 15
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
LIMS1 LIM and senescent cell antigen-like domains 1
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDGFA platelet-derived growth factor alpha polypeptide
PPAP2A phosphatidic acid phosphatase type 2A
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD23B RAD23 homolog B (S. cerevisiae)
SEPT9 septin 9
SFRP1 secreted frizzled-related protein 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1