BRD-K30743633_BL-073_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K30743633_BL-073_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
ALB albumin
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOD apolipoprotein D
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CD1E CD1e molecule
CD24 CD24 molecule
CD52 CD52 molecule
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
CTGF connective tissue growth factor
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNTT DNA nucleotidylexotransferase
FAM69A family with sequence similarity 69, member A
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
MMP2 matrix metallopeptidase 2
MZB1 marginal zone B and B1 cell-specific protein
NARFL nuclear prelamin A recognition factor-like
PEG10 paternally expressed 10
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SHB Src homology 2 domain containing adaptor protein B
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SNX7 sorting nexin 7
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMCC1 transmembrane and coiled-coil domain family 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)

decreased expression

Symbol Name
AHNAK AHNAK nucleoprotein
AQP3 aquaporin 3 (Gill blood group)
BTN3A2 butyrophilin, subfamily 3, member A2
CA12 carbonic anhydrase XII
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHL1 cell adhesion molecule L1-like
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
ECI2 enoyl-CoA delta isomerase 2
GNAS GNAS complex locus
GRB14 growth factor receptor-bound protein 14
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
LTF lactotransferrin
MACF1 microtubule-actin crosslinking factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MXRA5 matrix-remodelling associated 5
NAV3 neuron navigator 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRN1 neuritin 1
PI3 peptidase inhibitor 3, skin-derived
PTCH1 patched 1
S100A10 S100 calcium binding protein A10
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLIT2 slit homolog 2 (Drosophila)
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SORD sorbitol dehydrogenase
TFF1 trefoil factor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMBIM6 transmembrane BAX inhibitor motif containing 6
TPD52L1 tumor protein D52-like 1
TSPAN8 tetraspanin 8