BRD-K30632436_CTB_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K30632436_CTB_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLC Charcot-Leyden crystal galectin
CLIC3 chloride intracellular channel 3
CLU clusterin
CRELD2 cysteine-rich with EGF-like domains 2
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP2 dual specificity phosphatase 2
DUSP6 dual specificity phosphatase 6
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IL32 interleukin 32
KRT14 keratin 14, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
KYNU kynureninase
LY6E lymphocyte antigen 6 complex, locus E
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEGF9 multiple EGF-like-domains 9
NQO1 NAD(P)H dehydrogenase, quinone 1
PERP PERP, TP53 apoptosis effector
PGD phosphogluconate dehydrogenase
PI3 peptidase inhibitor 3, skin-derived
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLBD1 phospholipase B domain containing 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLPI secretory leukocyte peptidase inhibitor
SMAGP small cell adhesion glycoprotein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TRIM2 tripartite motif containing 2
TSKU tsukushi, small leucine rich proteoglycan
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VNN1 vanin 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACAT2 acetyl-CoA acetyltransferase 2
ACKR3 atypical chemokine receptor 3
ADAMDEC1 ADAM-like, decysin 1
AGR2 anterior gradient 2
AIM1 absent in melanoma 1
ARHGAP29 Rho GTPase activating protein 29
ASRGL1 asparaginase like 1
BCHE butyrylcholinesterase
BPHL biphenyl hydrolase-like (serine hydrolase)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CCNE2 cyclin E2
COL15A1 collagen, type XV, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A2 collagen, type V, alpha 2
CRABP1 cellular retinoic acid binding protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FGF13 fibroblast growth factor 13
FXYD6 FXYD domain containing ion transport regulator 6
GADD45B growth arrest and DNA-damage-inducible, beta
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
HAT1 histone acetyltransferase 1
IL1R1 interleukin 1 receptor, type I
NPTX2 neuronal pentraxin II
PEG3 paternally expressed 3
PLAU plasminogen activator, urokinase
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SOSTDC1 sclerostin domain containing 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SST somatostatin
TF transferrin
TFF1 trefoil factor 1
TMSB15A thymosin beta 15a
TUBB2A tubulin, beta 2A class IIa
WSB2 WD repeat and SOCS box containing 2
ZNF589 zinc finger protein 589