BRD-K30632436_CTB_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

86 genes differentially expressed following the BRD-K30632436_CTB_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BNC2 basonuclin 2
BST2 bone marrow stromal cell antigen 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRELD2 cysteine-rich with EGF-like domains 2
DDIT4 DNA-damage-inducible transcript 4
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DLK1 delta-like 1 homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
EFHC1 EF-hand domain (C-terminal) containing 1
FABP4 fatty acid binding protein 4, adipocyte
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAL histidine ammonia-lyase
HMOX1 heme oxygenase 1
INHBB inhibin, beta B
LIMS1 LIM and senescent cell antigen-like domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARCKS myristoylated alanine-rich protein kinase C substrate
MXRA8 matrix-remodelling associated 8
NAV2 neuron navigator 2
PDGFD platelet derived growth factor D
PEG3 paternally expressed 3
PIR pirin (iron-binding nuclear protein)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SEC31A SEC31 homolog A (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TALDO1 transaldolase 1
TBX3 T-box 3
TKT transketolase
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
VAT1 vesicle amine transport 1
VLDLR very low density lipoprotein receptor
WFS1 Wolfram syndrome 1 (wolframin)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
FABP7 fatty acid binding protein 7, brain
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LGALS1 lectin, galactoside-binding, soluble, 1
LMO4 LIM domain only 4
MGP matrix Gla protein
MMP2 matrix metallopeptidase 2
MXRA7 matrix-remodelling associated 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PRSS2 protease, serine, 2 (trypsin 2)
RAD51C RAD51 paralog C
RUNX3 runt-related transcription factor 3
S100A9 S100 calcium binding protein A9
SATB2 SATB homeobox 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TUBB6 tubulin, beta 6 class V