BRD-K29668683_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K29668683_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
C3ORF14 chromosome 3 open reading frame 14
CHN1 chimerin 1
CLGN calmegin
DEGS1 delta(4)-desaturase, sphingolipid 1
EXT1 exostosin glycosyltransferase 1
FGFR2 fibroblast growth factor receptor 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
HBB hemoglobin, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LAMP2 lysosomal-associated membrane protein 2
LOC100505650 uncharacterized LOC100505650
MECOM MDS1 and EVI1 complex locus
MUC16 mucin 16, cell surface associated
NPTX2 neuronal pentraxin II
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PPOX protoporphyrinogen oxidase
PTK2 protein tyrosine kinase 2
PTPRF protein tyrosine phosphatase, receptor type, F
QPCT glutaminyl-peptide cyclotransferase
RAI14 retinoic acid induced 14
RND3 Rho family GTPase 3
RPA2 replication protein A2, 32kDa
S100A8 S100 calcium binding protein A8
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SNX13 sorting nexin 13
SPRED2 sprouty-related, EVH1 domain containing 2
SRGN serglycin
SSBP2 single-stranded DNA binding protein 2
STK26 serine/threonine protein kinase 26
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIM2 tripartite motif containing 2
TUSC3 tumor suppressor candidate 3
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CA12 carbonic anhydrase XII
CDA cytidine deaminase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRIP1 cysteine-rich protein 1 (intestinal)
FOSL1 FOS-like antigen 1
GMDS GDP-mannose 4,6-dehydratase
IFRD2 interferon-related developmental regulator 2
KCTD12 potassium channel tetramerization domain containing 12
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MUC5B mucin 5B, oligomeric mucus/gel-forming
NRIP1 nuclear receptor interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTX3 pentraxin 3, long
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SET SET nuclear proto-oncogene
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPATS2L spermatogenesis associated, serine-rich 2-like
STOM stomatin
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNPO1 transportin 1
WSB1 WD repeat and SOCS box containing 1
ZNF131 zinc finger protein 131