BRD-K29395450_PIK-93_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K29395450_PIK-93_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADGRG6 adhesion G protein-coupled receptor G6
ALOX5 arachidonate 5-lipoxygenase
CPM carboxypeptidase M
DES desmin
GRB7 growth factor receptor-bound protein 7
GULP1 GULP, engulfment adaptor PTB domain containing 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KIAA0355 KIAA0355
LDB3 LIM domain binding 3
LTBP3 latent transforming growth factor beta binding protein 3
MYRF myelin regulatory factor
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PEG10 paternally expressed 10
PLA2G15 phospholipase A2, group XV
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLS1 plastin 1
RGS5 regulator of G-protein signaling 5
SPON1 spondin 1, extracellular matrix protein
SPP1 secreted phosphoprotein 1
TMEM47 transmembrane protein 47
TNS3 tensin 3
TPD52L1 tumor protein D52-like 1
TSC22D3 TSC22 domain family, member 3
VCAN versican
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
APOD apolipoprotein D
CCND1 cyclin D1
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLTB clathrin, light chain B
CST1 cystatin SN
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FST follistatin
GBP1 guanylate binding protein 1, interferon-inducible
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGL immunoglobulin lambda locus
JADE2 jade family PHD finger 2
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MSMO1 methylsterol monooxygenase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOX9 SRY (sex determining region Y)-box 9
SPRR1A small proline-rich protein 1A
SQLE squalene epoxidase
TRIB3 tribbles pseudokinase 3