BRD-K29395450_PIK-93_SKBR3_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K29395450_PIK-93_SKBR3_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUTS2 autism susceptibility candidate 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BZW2 basic leucine zipper and W2 domains 2
CADM1 cell adhesion molecule 1
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CPD carboxypeptidase D
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
DENND2D DENN/MADD domain containing 2D
DSP desmoplakin
EPHB2 EPH receptor B2
GCLC glutamate-cysteine ligase, catalytic subunit
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IRF7 interferon regulatory factor 7
KAT6B K(lysine) acetyltransferase 6B
KDM3A lysine (K)-specific demethylase 3A
KIAA0355 KIAA0355
KIF20A kinesin family member 20A
LYPD1 LY6/PLAUR domain containing 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
N4BP2L2 NEDD4 binding protein 2-like 2
NOTCH2NL notch 2 N-terminal like
NPIPB3 nuclear pore complex interacting protein family, member B3
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PEG10 paternally expressed 10
PLAGL1 pleiomorphic adenoma gene-like 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SGCE sarcoglycan, epsilon
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STC2 stanniocalcin 2
STX1A syntaxin 1A (brain)
TNS3 tensin 3
TRA2A transformer 2 alpha homolog (Drosophila)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
WSB1 WD repeat and SOCS box containing 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
CAV2 caveolin 2
CCND1 cyclin D1
CCND2 cyclin D2
COL15A1 collagen, type XV, alpha 1
COX7C cytochrome c oxidase subunit VIIc
DHCR7 7-dehydrocholesterol reductase
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGR2 early growth response 2
FABP4 fatty acid binding protein 4, adipocyte
FLNA filamin A, alpha
FTH1 ferritin, heavy polypeptide 1
GAS1 growth arrest-specific 1
HBB hemoglobin, beta
IL32 interleukin 32
INSIG1 insulin induced gene 1
LY96 lymphocyte antigen 96
MAOB monoamine oxidase B
MEIS1 Meis homeobox 1
MID1IP1 MID1 interacting protein 1
PLN phospholamban
PRKCB protein kinase C, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TIMP1 TIMP metallopeptidase inhibitor 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZYX zyxin