BRD-K29395450_PIK-93_MDAMB231_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K29395450_PIK-93_MDAMB231_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADD3 adducin 3 (gamma)
AKR1C1 aldo-keto reductase family 1, member C1
ATF4 activating transcription factor 4
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
C8ORF4 chromosome 8 open reading frame 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLEC2B C-type lectin domain family 2, member B
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
GADD45B growth arrest and DNA-damage-inducible, beta
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KIAA0226L KIAA0226-like
LASP1 LIM and SH3 protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEG3 maternally expressed 3 (non-protein coding)
MMD monocyte to macrophage differentiation-associated
MT1M metallothionein 1M
PAX5 paired box 5
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POU2AF1 POU class 2 associating factor 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RGS4 regulator of G-protein signaling 4
RTN1 reticulon 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
SST somatostatin
STX1A syntaxin 1A (brain)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCL1A T-cell leukemia/lymphoma 1A
TESC tescalcin
TMC5 transmembrane channel-like 5
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
WSB1 WD repeat and SOCS box containing 1
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
BEX4 brain expressed, X-linked 4
CCNE1 cyclin E1
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DHCR7 7-dehydrocholesterol reductase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPB8 heat shock 22kDa protein 8
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KANK1 KN motif and ankyrin repeat domains 1
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PFN2 profilin 2
PI3 peptidase inhibitor 3, skin-derived
RCAN1 regulator of calcineurin 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SCRG1 stimulator of chondrogenesis 1
SELL selectin L
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TBX2 T-box 2
TES testin LIM domain protein
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VCAM1 vascular cell adhesion molecule 1