BRD-K29395450_PIK-93_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K29395450_PIK-93_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BEX1 brain expressed, X-linked 1
C6ORF48 chromosome 6 open reading frame 48
CCNG2 cyclin G2
CST3 cystatin C
CXCL14 chemokine (C-X-C motif) ligand 14
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
FOXO4 forkhead box O4
GADD45B growth arrest and DNA-damage-inducible, beta
HBP1 HMG-box transcription factor 1
KDM3A lysine (K)-specific demethylase 3A
NEFL neurofilament, light polypeptide
NPTX2 neuronal pentraxin II
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QPCT glutaminyl-peptide cyclotransferase
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RNMT RNA (guanine-7-) methyltransferase
SLCO1B3 solute carrier organic anion transporter family, member 1B3
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK1 adenylate kinase 1
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAPN1 calpain 1, (mu/I) large subunit
CHPT1 choline phosphotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL6A2 collagen, type VI, alpha 2
CRYAB crystallin, alpha B
DHCR7 7-dehydrocholesterol reductase
DNM1L dynamin 1-like
DPP4 dipeptidyl-peptidase 4
EBP emopamil binding protein (sterol isomerase)
EGFR epidermal growth factor receptor
GCH1 GTP cyclohydrolase 1
GYG1 glycogenin 1
HIST1H4C histone cluster 1, H4c
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MYLK myosin light chain kinase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NXN nucleoredoxin
PLS3 plastin 3
RANBP1 RAN binding protein 1
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFN stratifin
TAGLN transgelin
TUBB6 tubulin, beta 6 class V