BRD-K29395450_PIK-93_MCF7_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K29395450_PIK-93_MCF7_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL5 chemokine (C-C motif) ligand 5
COL9A2 collagen, type IX, alpha 2
CPE carboxypeptidase E
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYR61 cysteine-rich, angiogenic inducer, 61
EGFL6 EGF-like-domain, multiple 6
EMP2 epithelial membrane protein 2
FAS Fas cell surface death receptor
LRRC16A leucine rich repeat containing 16A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAMLD1 mastermind-like domain containing 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-1 NK3 homeobox 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHOBTB3 Rho-related BTB domain containing 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A10 S100 calcium binding protein A10
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPP1 secreted phosphoprotein 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ANXA1 annexin A1
APOD apolipoprotein D
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BID BH3 interacting domain death agonist
BOP1 block of proliferation 1
CYC1 cytochrome c-1
EXOSC4 exosome component 4
GRIA2 glutamate receptor, ionotropic, AMPA 2
HOXB6 homeobox B6
JAG1 jagged 1
LST1 leukocyte specific transcript 1
LY6E lymphocyte antigen 6 complex, locus E
NR2F6 nuclear receptor subfamily 2, group F, member 6
PTP4A3 protein tyrosine phosphatase type IVA, member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SOX9 SRY (sex determining region Y)-box 9
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)