BRD-K29395450_PIK-93_MCF10A_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K29395450_PIK-93_MCF10A_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ATF3 activating transcription factor 3
C6ORF48 chromosome 6 open reading frame 48
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD24 CD24 molecule
CFD complement factor D (adipsin)
CFH complement factor H
CRYM crystallin, mu
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPT dermatopontin
FBN1 fibrillin 1
FGFR2 fibroblast growth factor receptor 2
FSTL1 follistatin-like 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GADD45B growth arrest and DNA-damage-inducible, beta
GOLM1 golgi membrane protein 1
GPX3 glutathione peroxidase 3
HBP1 HMG-box transcription factor 1
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KIAA0907 KIAA0907
KLF6 Kruppel-like factor 6
LPL lipoprotein lipase
MKNK2 MAP kinase interacting serine/threonine kinase 2
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTK2 protein tyrosine kinase 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SRGN serglycin
STX1A syntaxin 1A (brain)
SYNE2 spectrin repeat containing, nuclear envelope 2
TMSB15A thymosin beta 15a
TSC22D3 TSC22 domain family, member 3
TSPO translocator protein (18kDa)
TUFT1 tuftelin 1

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ANPEP alanyl (membrane) aminopeptidase
BHLHE41 basic helix-loop-helix family, member e41
COL18A1 collagen, type XVIII, alpha 1
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
EFNB2 ephrin-B2
EGR1 early growth response 1
EGR3 early growth response 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENDOD1 endonuclease domain containing 1
FABP7 fatty acid binding protein 7, brain
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HHEX hematopoietically expressed homeobox
IL1B interleukin 1, beta
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LAMA3 laminin, alpha 3
LAPTM4B lysosomal protein transmembrane 4 beta
LEF1 lymphoid enhancer-binding factor 1
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MMP9 matrix metallopeptidase 9
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RBP1 retinol binding protein 1, cellular
SELL selectin L
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
TBX2 T-box 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
XIST X inactive specific transcript (non-protein coding)