BRD-K29395450_PIK-93_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K29395450_PIK-93_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOB apolipoprotein B
APOD apolipoprotein D
BANK1 B-cell scaffold protein with ankyrin repeats 1
C14ORF132 chromosome 14 open reading frame 132
C6ORF48 chromosome 6 open reading frame 48
CLU clusterin
COL4A5 collagen, type IV, alpha 5
DDIT3 DNA-damage-inducible transcript 3
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DUSP22 dual specificity phosphatase 22
DUSP6 dual specificity phosphatase 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EVI2A ecotropic viral integration site 2A
FBN1 fibrillin 1
FGF13 fibroblast growth factor 13
FN1 fibronectin 1
FOXO4 forkhead box O4
GAGE3 G antigen 3
GATA3 GATA binding protein 3
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GPC3 glypican 3
GSTM3 glutathione S-transferase mu 3 (brain)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HEPH hephaestin
IQGAP1 IQ motif containing GTPase activating protein 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA1033 KIAA1033
LAMA2 laminin, alpha 2
LPAR1 lysophosphatidic acid receptor 1
LTBP1 latent transforming growth factor beta binding protein 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MT1M metallothionein 1M
NBPF10 neuroblastoma breakpoint family, member 10
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG3 paternally expressed 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
S100P S100 calcium binding protein P
SCD5 stearoyl-CoA desaturase 5
SCG5 secretogranin V
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPAG4 sperm associated antigen 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRPX sushi-repeat containing protein, X-linked
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
TFF1 trefoil factor 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNC tenascin C
TOP1 topoisomerase (DNA) I
TXNIP thioredoxin interacting protein
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
AQP3 aquaporin 3 (Gill blood group)
ASCC3 activating signal cointegrator 1 complex subunit 3
BIRC2 baculoviral IAP repeat containing 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CYB5A cytochrome b5 type A (microsomal)
FEN1 flap structure-specific endonuclease 1
GALE UDP-galactose-4-epimerase
GBP1 guanylate binding protein 1, interferon-inducible
HIST1H4C histone cluster 1, H4c
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KIF1BP KIF1 binding protein
KLK11 kallikrein-related peptidase 11
LAMP3 lysosomal-associated membrane protein 3
LIG1 ligase I, DNA, ATP-dependent
NET1 neuroepithelial cell transforming 1
PDLIM5 PDZ and LIM domain 5
PRKCH protein kinase C, eta
RFC2 replication factor C (activator 1) 2, 40kDa
RGS1 regulator of G-protein signaling 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
TUBB4B tubulin, beta 4B class IVb