BRD-K29395450_PIK-93_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K29395450_PIK-93_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CAB39 calcium binding protein 39
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD38 CD38 molecule
CFB complement factor B
CP ceruloplasmin (ferroxidase)
CTGF connective tissue growth factor
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPP4 dipeptidyl-peptidase 4
EHD3 EH-domain containing 3
EPAS1 endothelial PAS domain protein 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FN1 fibronectin 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLS glutaminase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LEPR leptin receptor
LIMCH1 LIM and calponin homology domains 1
MAOA monoamine oxidase A
MSMB microseminoprotein, beta-
MYH10 myosin, heavy chain 10, non-muscle
MZB1 marginal zone B and B1 cell-specific protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
P3H2 prolyl 3-hydroxylase 2
PDHX pyruvate dehydrogenase complex, component X
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRUNE2 prune homolog 2 (Drosophila)
PYCARD PYD and CARD domain containing
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC38A2 solute carrier family 38, member 2
SMAD3 SMAD family member 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
TARP TCR gamma alternate reading frame protein
TF transferrin
TGFA transforming growth factor, alpha
TPD52 tumor protein D52
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
CDC42 cell division cycle 42
CLU clusterin
COL13A1 collagen, type XIII, alpha 1
COL3A1 collagen, type III, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYNLT1 dynein, light chain, Tctex-type 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPM6B glycoprotein M6B
HOXB6 homeobox B6
IFI27 interferon, alpha-inducible protein 27
LTF lactotransferrin
MARCKSL1 MARCKS-like 1
MYLK myosin light chain kinase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PODXL podocalyxin-like
S100A7 S100 calcium binding protein A7
SFN stratifin
TMEM158 transmembrane protein 158 (gene/pseudogene)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)