BRD-K29395450_PIK-93_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K29395450_PIK-93_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AHNAK2 AHNAK nucleoprotein 2
ARID5B AT rich interactive domain 5B (MRF1-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHN1 chimerin 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FZD10 frizzled class receptor 10
GPM6B glycoprotein M6B
HEBP2 heme binding protein 2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
MGP matrix Gla protein
MMP10 matrix metallopeptidase 10
MX2 MX dynamin-like GTPase 2
PDGFRL platelet-derived growth factor receptor-like
PLAT plasminogen activator, tissue
RAB21 RAB21, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
TBC1D15 TBC1 domain family, member 15
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMX4 thioredoxin-related transmembrane protein 4
VAV3 vav 3 guanine nucleotide exchange factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CA2 carbonic anhydrase II
CAPN2 calpain 2, (m/II) large subunit
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A2 collagen, type IV, alpha 2
CTSS cathepsin S
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HACD1 3-hydroxyacyl-CoA dehydratase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
JAG1 jagged 1
JMJD6 jumonji domain containing 6
LAPTM4B lysosomal protein transmembrane 4 beta
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC39A14 solute carrier family 39 (zinc transporter), member 14
TARP TCR gamma alternate reading frame protein