BRD-K29395450_PIK-93_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

95 genes differentially expressed following the BRD-K29395450_PIK-93_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD4 abhydrolase domain containing 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFH complement factor H
CLEC2B C-type lectin domain family 2, member B
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLU clusterin
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN3 endothelin 3
EFNA1 ephrin-A1
ERAP2 endoplasmic reticulum aminopeptidase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GBP2 guanylate binding protein 2, interferon-inducible
GNS glucosamine (N-acetyl)-6-sulfatase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GUSBP3 glucuronidase, beta pseudogene 3
HBP1 HMG-box transcription factor 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
KDM3A lysine (K)-specific demethylase 3A
KIAA1033 KIAA1033
KLHL24 kelch-like family member 24
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS8 lectin, galactoside-binding, soluble, 8
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN2A1 mannosidase, alpha, class 2A, member 1
MGP matrix Gla protein
MTUS1 microtubule associated tumor suppressor 1
MX2 MX dynamin-like GTPase 2
MYO6 myosin VI
NFIB nuclear factor I/B
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PRAME preferentially expressed antigen in melanoma
PSPH phosphoserine phosphatase
PTCH1 patched 1
RAB40B RAB40B, member RAS oncogene family
RB1CC1 RB1-inducible coiled-coil 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STX1A syntaxin 1A (brain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN8 tetraspanin 8
TXNL4B thioredoxin-like 4B
VTCN1 V-set domain containing T cell activation inhibitor 1
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CCDC86 coiled-coil domain containing 86
CD24 CD24 molecule
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COLEC12 collectin sub-family member 12
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFNB2 ephrin-B2
EMP2 epithelial membrane protein 2
EPHA2 EPH receptor A2
G0S2 G0/G1 switch 2
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
HAS2 hyaluronan synthase 2
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
JAG1 jagged 1
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MAT2A methionine adenosyltransferase II, alpha
NKX3-1 NK3 homeobox 1
PNP purine nucleoside phosphorylase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PYCARD PYD and CARD domain containing
RGCC regulator of cell cycle
RPA3 replication protein A3, 14kDa
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERTAD2 SERTA domain containing 2
SNAI2 snail family zinc finger 2
SOWAHC sosondowah ankyrin repeat domain family member C
SQLE squalene epoxidase
TFPI2 tissue factor pathway inhibitor 2
TNC tenascin C
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2