BRD-K28307902_Flutamide_VCAP_24.0_h_28.96_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K28307902_Flutamide_VCAP_24.0_h_28.96_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
BAMBI BMP and activin membrane-bound inhibitor
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CST1 cystatin SN
CXADR coxsackie virus and adenovirus receptor
GREM1 gremlin 1, DAN family BMP antagonist
IGFBP3 insulin-like growth factor binding protein 3
MTSS1 metastasis suppressor 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SESN1 sestrin 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TMEM45A transmembrane protein 45A

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND1 cyclin D1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
GCH1 GTP cyclohydrolase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOMER2 homer scaffolding protein 2
IGF1R insulin-like growth factor 1 receptor
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
NKX3-1 NK3 homeobox 1