BRD-K28307902_Flutamide_MCF7_24.0_h_28.96_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K28307902_Flutamide_MCF7_24.0_h_28.96_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
CBS cystathionine-beta-synthase
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DDIT4 DNA-damage-inducible transcript 4
DMD dystrophin
HIST1H1C histone cluster 1, H1c
KRT15 keratin 15, type I
LRMP lymphoid-restricted membrane protein
MEF2C myocyte enhancer factor 2C
NFE2L3 nuclear factor, erythroid 2-like 3
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CAST calpastatin
CCNB2 cyclin B2
CYB561 cytochrome b561
CYC1 cytochrome c-1
DLD dihydrolipoamide dehydrogenase
PLK1 polo-like kinase 1
PURA purine-rich element binding protein A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
TPM4 tropomyosin 4
TUBB6 tubulin, beta 6 class V
TYMS thymidylate synthetase
UBL3 ubiquitin-like 3