BRD-K28307902_Flutamide_CL34_6.0_h_28.96_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

131 genes differentially expressed following the BRD-K28307902_Flutamide_CL34_6.0_h_28.96_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTC1 actin, alpha, cardiac muscle 1
AUTS2 autism susceptibility candidate 2
C6ORF62 chromosome 6 open reading frame 62
CALB1 calbindin 1, 28kDa
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CFD complement factor D (adipsin)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLC Charcot-Leyden crystal galectin
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
EFHD1 EF-hand domain family, member D1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
FHOD3 formin homology 2 domain containing 3
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA3 GATA binding protein 3
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
H2AFV H2A histone family, member V
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HOMER3 homer scaffolding protein 3
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT19 keratin 19, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEF2C myocyte enhancer factor 2C
MEIS2 Meis homeobox 2
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDE8B phosphodiesterase 8B
PDGFRL platelet-derived growth factor receptor-like
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PEX11A peroxisomal biogenesis factor 11 alpha
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRD protein tyrosine phosphatase, receptor type, D
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SCD5 stearoyl-CoA desaturase 5
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPARCL1 SPARC-like 1 (hevin)
SRGN serglycin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAR steroidogenic acute regulatory protein
SULF1 sulfatase 1
TES testin LIM domain protein
TF transferrin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGIF1 TGFB-induced factor homeobox 1
TLK2 tousled-like kinase 2
TM6SF1 transmembrane 6 superfamily member 1
TPM4 tropomyosin 4
TPMT thiopurine S-methyltransferase
UGP2 UDP-glucose pyrophosphorylase 2
VLDLR very low density lipoprotein receptor
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ADGRE5 adhesion G protein-coupled receptor E5
AK1 adenylate kinase 1
ARFIP2 ADP-ribosylation factor interacting protein 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
CCNA2 cyclin A2
CCND1 cyclin D1
CDA cytidine deaminase
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
EI24 etoposide induced 2.4
EXOSC4 exosome component 4
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
GRWD1 glutamate-rich WD repeat containing 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IL13RA2 interleukin 13 receptor, alpha 2
INSIG1 insulin induced gene 1
KEAP1 kelch-like ECH-associated protein 1
LAMB3 laminin, beta 3
LDLR low density lipoprotein receptor
LUC7L3 LUC7-like 3 (S. cerevisiae)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYH10 myosin, heavy chain 10, non-muscle
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
OXA1L oxidase (cytochrome c) assembly 1-like
PARP2 poly (ADP-ribose) polymerase 2
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLK1 polo-like kinase 1
PNKP polynucleotide kinase 3'-phosphatase
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRDX2 peroxiredoxin 2
PRDX4 peroxiredoxin 4
PROM1 prominin 1
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFF3 trefoil factor 3 (intestinal)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNIP1 TNFAIP3 interacting protein 1
TOP1 topoisomerase (DNA) I
TSPAN3 tetraspanin 3
TSPAN8 tetraspanin 8