BRD-K27737647_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K27737647_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BHLHE41 basic helix-loop-helix family, member e41
C1ORF115 chromosome 1 open reading frame 115
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD52 CD52 molecule
CRIP2 cysteine-rich protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT4 DNA-damage-inducible transcript 4
DUSP2 dual specificity phosphatase 2
EPHA3 EPH receptor A3
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FXYD2 FXYD domain containing ion transport regulator 2
GCA grancalcin, EF-hand calcium binding protein
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPM6A glycoprotein M6A
GUSBP3 glucuronidase, beta pseudogene 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
NRN1 neuritin 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
STC2 stanniocalcin 2
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VAV3 vav 3 guanine nucleotide exchange factor
VIM vimentin
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
AKR1C2 aldo-keto reductase family 1, member C2
CDC20 cell division cycle 20
EXOSC4 exosome component 4
F3 coagulation factor III (thromboplastin, tissue factor)
FILIP1L filamin A interacting protein 1-like
FOXO1 forkhead box O1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLK5 kallikrein-related peptidase 5
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
MATN2 matrilin 2
MIR22HG MIR22 host gene
MMD monocyte to macrophage differentiation-associated
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MXRA5 matrix-remodelling associated 5
PBX3 pre-B-cell leukemia homeobox 3
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
RHOBTB3 Rho-related BTB domain containing 3
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFRP4 secreted frizzled-related protein 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLPI secretory leukocyte peptidase inhibitor
SOX4 SRY (sex determining region Y)-box 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TFF1 trefoil factor 1
TMOD1 tropomodulin 1
VAMP8 vesicle-associated membrane protein 8
VCAN versican
ZBED2 zinc finger, BED-type containing 2