BRD-K27316855_1,25-DIHYDROXYVITAMIN D3_HCC515_6.0_h_1.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K27316855_1,25-DIHYDROXYVITAMIN D3_HCC515_6.0_h_1.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
C1QA complement component 1, q subcomponent, A chain
CAPG capping protein (actin filament), gelsolin-like
CLDN3 claudin 3
CLDN4 claudin 4
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COL6A3 collagen, type VI, alpha 3
COLEC12 collectin sub-family member 12
CP ceruloplasmin (ferroxidase)
CSTA cystatin A (stefin A)
CTSH cathepsin H
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
DPP4 dipeptidyl-peptidase 4
FXYD6 FXYD domain containing ion transport regulator 6
HIST1H1C histone cluster 1, H1c
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
KLK11 kallikrein-related peptidase 11
MEIS2 Meis homeobox 2
NXN nucleoredoxin
PERP PERP, TP53 apoptosis effector
RGS1 regulator of G-protein signaling 1
S100A8 S100 calcium binding protein A8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
TMSB15A thymosin beta 15a
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ANXA5 annexin A5
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BRD2 bromodomain containing 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EIF5 eukaryotic translation initiation factor 5
ELF1 E74-like factor 1 (ets domain transcription factor)
FAM46A family with sequence similarity 46, member A
PCDH9 protocadherin 9
RBMS1 RNA binding motif, single stranded interacting protein 1
SRRM2 serine/arginine repetitive matrix 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TPBG trophoblast glycoprotein
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta