BRD-K27316855_1,25-DIHYDROXYVITAMIN D3_HA1E_24.0_h_1.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K27316855_1,25-DIHYDROXYVITAMIN D3_HA1E_24.0_h_1.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTC1 actin, alpha, cardiac muscle 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CD14 CD14 molecule
CRABP2 cellular retinoic acid binding protein 2
ENO2 enolase 2 (gamma, neuronal)
FBN2 fibrillin 2
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
GCLC glutamate-cysteine ligase, catalytic subunit
GLUL glutamate-ammonia ligase
IL1RN interleukin 1 receptor antagonist
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KRT6A keratin 6A, type II
LAPTM5 lysosomal protein transmembrane 5
LGALS8 lectin, galactoside-binding, soluble, 8
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MEIS2 Meis homeobox 2
NXN nucleoredoxin
PPARD peroxisome proliferator-activated receptor delta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RXRA retinoid X receptor, alpha
SCEL sciellin
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPB surfactant protein B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADI1 acireductone dioxygenase 1
ADIRF adipogenesis regulatory factor
ALDOB aldolase B, fructose-bisphosphate
ANXA5 annexin A5
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
CCDC109B coiled-coil domain containing 109B
CDC14B cell division cycle 14B
CDH17 cadherin 17, LI cadherin (liver-intestine)
CLC Charcot-Leyden crystal galectin
CLU clusterin
COL14A1 collagen, type XIV, alpha 1
COMP cartilage oligomeric matrix protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYCS cytochrome c, somatic
CYTIP cytohesin 1 interacting protein
ELANE elastase, neutrophil expressed
FBN1 fibrillin 1
FKBP14 FK506 binding protein 14, 22 kDa
G0S2 G0/G1 switch 2
HACD2 3-hydroxyacyl-CoA dehydratase 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
ITGAV integrin, alpha V
ITGB1BP1 integrin beta 1 binding protein 1
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
LGALS4 lectin, galactoside-binding, soluble, 4
LY75 lymphocyte antigen 75
MAB21L2 mab-21-like 2 (C. elegans)
MAGEA3 melanoma antigen family A3
MBNL1 muscleblind-like splicing regulator 1
MPO myeloperoxidase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLAC8 placenta-specific 8
PLLP plasmolipin
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRSS3 protease, serine, 3
PTPRK protein tyrosine phosphatase, receptor type, K
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
SC5D sterol-C5-desaturase
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SFRP4 secreted frizzled-related protein 4
SPINK1 serine peptidase inhibitor, Kazal type 1
THAP11 THAP domain containing 11
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TOB1 transducer of ERBB2, 1
TSPAN8 tetraspanin 8
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble