BRD-K26838195_AST1306_HT29_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K26838195_AST1306_HT29_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
ANXA1 annexin A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
C2CD5 C2 calcium-dependent domain containing 5
CAPG capping protein (actin filament), gelsolin-like
CBS cystathionine-beta-synthase
CCDC92 coiled-coil domain containing 92
CD24 CD24 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM13A family with sequence similarity 13, member A
FBN2 fibrillin 2
FCGBP Fc fragment of IgG binding protein
FOXO4 forkhead box O4
FZD2 frizzled class receptor 2
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GOLM1 golgi membrane protein 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MID1 midline 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVP major vault protein
MXRA7 matrix-remodelling associated 7
MYLK myosin light chain kinase
NEFL neurofilament, light polypeptide
NUPR1 nuclear protein, transcriptional regulator, 1
OBSL1 obscurin-like 1
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PNMAL1 paraneoplastic Ma antigen family-like 1
PROM1 prominin 1
PRUNE2 prune homolog 2 (Drosophila)
QPCT glutaminyl-peptide cyclotransferase
RAP1GAP RAP1 GTPase activating protein
REG1A regenerating islet-derived 1 alpha
S100A11 S100 calcium binding protein A11
SGK1 serum/glucocorticoid regulated kinase 1
SH3YL1 SH3 and SYLF domain containing 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT1 signal transducer and activator of transcription 1, 91kDa
SYNE2 spectrin repeat containing, nuclear envelope 2
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TIMP1 TIMP metallopeptidase inhibitor 1
TSPO translocator protein (18kDa)
TUBA1A tubulin, alpha 1a
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VIM vimentin
WBP5 WW domain binding protein 5
YPEL5 yippee-like 5 (Drosophila)
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AREG amphiregulin
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CCND1 cyclin D1
CDK1 cyclin-dependent kinase 1
CENPU centromere protein U
DCK deoxycytidine kinase
EGR3 early growth response 3
ENO1 enolase 1, (alpha)
EREG epiregulin
FOSL1 FOS-like antigen 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HBB hemoglobin, beta
MALL mal, T-cell differentiation protein-like
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PARP2 poly (ADP-ribose) polymerase 2
PCNA proliferating cell nuclear antigen
PDLIM1 PDZ and LIM domain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPAT phosphoribosyl pyrophosphate amidotransferase
RRM1 ribonucleotide reductase M1
SMAD1 SMAD family member 1
SPON1 spondin 1, extracellular matrix protein
TMPO thymopoietin
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TUBB2A tubulin, beta 2A class IIa
XPO7 exportin 7