BRD-K26760349_HG-9-91-01_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

52 genes differentially expressed following the BRD-K26760349_HG-9-91-01_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
CALML4 calmodulin-like 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN3 claudin 3
DPYSL3 dihydropyrimidinase-like 3
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
IRS2 insulin receptor substrate 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MUC4 mucin 4, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
RBPMS RNA binding protein with multiple splicing
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RTN3 reticulon 3
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRSF6 serine/arginine-rich splicing factor 6
ST18 suppression of tumorigenicity 18, zinc finger
TSKU tsukushi, small leucine rich proteoglycan
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
C1ORF115 chromosome 1 open reading frame 115
C2CD5 C2 calcium-dependent domain containing 5
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DMD dystrophin
DNM1L dynamin 1-like
EPS8 epidermal growth factor receptor pathway substrate 8
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
KRT7 keratin 7, type II
LGALS3 lectin, galactoside-binding, soluble, 3
LTF lactotransferrin
MMP7 matrix metallopeptidase 7
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
PEG3 paternally expressed 3
RAD51C RAD51 paralog C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
STAB1 stabilin 1
TACSTD2 tumor-associated calcium signal transducer 2
THAP11 THAP domain containing 11
VDAC1 voltage-dependent anion channel 1