BRD-K26756394_VE821_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K26756394_VE821_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CAPG capping protein (actin filament), gelsolin-like
CD44 CD44 molecule (Indian blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPY3 canopy FGF signaling regulator 3
CYB5A cytochrome b5 type A (microsomal)
DEFB1 defensin, beta 1
HOOK2 hook microtubule-tethering protein 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
SOX11 SRY (sex determining region Y)-box 11
TRIP6 thyroid hormone receptor interactor 6

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CPE carboxypeptidase E
GLIPR1 GLI pathogenesis-related 1
IFI27 interferon, alpha-inducible protein 27
MGLL monoglyceride lipase
MSMB microseminoprotein, beta-
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1