BRD-K26015241_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K26015241_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ARMCX2 armadillo repeat containing, X-linked 2
ARMCX6 armadillo repeat containing, X-linked 6
C3ORF14 chromosome 3 open reading frame 14
CAST calpastatin
CD200 CD200 molecule
CHMP4A charged multivesicular body protein 4A
CLGN calmegin
CPM carboxypeptidase M
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FBXO34 F-box protein 34
GATA3 GATA binding protein 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HES1 hes family bHLH transcription factor 1
ICAM2 intercellular adhesion molecule 2
IL7R interleukin 7 receptor
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
KYNU kynureninase
LDOC1 leucine zipper, down-regulated in cancer 1
MTSS1 metastasis suppressor 1
NPY neuropeptide Y
OLFM4 olfactomedin 4
PDGFRL platelet-derived growth factor receptor-like
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PPARG peroxisome proliferator-activated receptor gamma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTN pleiotrophin
QPCT glutaminyl-peptide cyclotransferase
RAP1GAP RAP1 GTPase activating protein
SCGB1D2 secretoglobin, family 1D, member 2
SH3BGRL SH3 domain binding glutamate-rich protein like
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM251 transmembrane protein 251
TUBA1A tubulin, alpha 1a
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK4 adenylate kinase 4
APOA1 apolipoprotein A-I
APOE apolipoprotein E
BCL6 B-cell CLL/lymphoma 6
CA2 carbonic anhydrase II
CANX calnexin
CDV3 CDV3 homolog (mouse)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTSH cathepsin H
DMD dystrophin
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5A eukaryotic translation initiation factor 5A
ERAP2 endoplasmic reticulum aminopeptidase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FKSG49 FKSG49
FLNA filamin A, alpha
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IFRD2 interferon-related developmental regulator 2
IL1R2 interleukin 1 receptor, type II
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
LASP1 LIM and SH3 protein 1
LYPLA1 lysophospholipase I
MACF1 microtubule-actin crosslinking factor 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MGP matrix Gla protein
MRPL12 mitochondrial ribosomal protein L12
NEBL nebulette
PEBP1 phosphatidylethanolamine binding protein 1
PEG3 paternally expressed 3
PLP1 proteolipid protein 1
PRDX2 peroxiredoxin 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TF transferrin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TNNC1 troponin C type 1 (slow)
WDR1 WD repeat domain 1
WSB1 WD repeat and SOCS box containing 1