BRD-K25340465_OSI-930_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K25340465_OSI-930_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOA aldolase A, fructose-bisphosphate
ASPH aspartate beta-hydroxylase
CALML5 calmodulin-like 5
CELF2 CUGBP, Elav-like family member 2
COL6A3 collagen, type VI, alpha 3
CRISP3 cysteine-rich secretory protein 3
CST7 cystatin F (leukocystatin)
CXCL9 chemokine (C-X-C motif) ligand 9
DUSP4 dual specificity phosphatase 4
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOSL1 FOS-like antigen 1
FST follistatin
GBP2 guanylate binding protein 2, interferon-inducible
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
GRB10 growth factor receptor-bound protein 10
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LIF leukemia inhibitory factor
LOXL1 lysyl oxidase-like 1
LTF lactotransferrin
MAOB monoamine oxidase B
MYLK myosin light chain kinase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIP prolactin-induced protein
PKM pyruvate kinase, muscle
POSTN periostin, osteoblast specific factor
RPS4Y1 ribosomal protein S4, Y-linked 1
S100P S100 calcium binding protein P
SETBP1 SET binding protein 1
SOD2 superoxide dismutase 2, mitochondrial
SRSF6 serine/arginine-rich splicing factor 6
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THBS1 thrombospondin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
CEMIP cell migration inducing protein, hyaluronan binding
CREM cAMP responsive element modulator
CXADR coxsackie virus and adenovirus receptor
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EPHA3 EPH receptor A3
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GHR growth hormone receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPER1 G protein-coupled estrogen receptor 1
GSTA4 glutathione S-transferase alpha 4
H2BFS H2B histone family, member S (pseudogene)
HEBP1 heme binding protein 1
HIST1H2BK histone cluster 1, H2bk
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIAA1467 KIAA1467
LAGE3 L antigen family, member 3
MAP2K6 mitogen-activated protein kinase kinase 6
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MEOX2 mesenchyme homeobox 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SELL selectin L
SGK1 serum/glucocorticoid regulated kinase 1
SORD sorbitol dehydrogenase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON1 spondin 1, extracellular matrix protein
TGFBI transforming growth factor, beta-induced, 68kDa
TPBG trophoblast glycoprotein
TSC22D1 TSC22 domain family, member 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon