BRD-K25340465_OSI-930_MCF7_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K25340465_OSI-930_MCF7_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ASPN asporin
BMP7 bone morphogenetic protein 7
CALB1 calbindin 1, 28kDa
CCR2 chemokine (C-C motif) receptor 2
CD93 CD93 molecule
COTL1 coactosin-like F-actin binding protein 1
CTGF connective tissue growth factor
CTSH cathepsin H
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP4 dual specificity phosphatase 4
F13A1 coagulation factor XIII, A1 polypeptide
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
GLS glutaminase
GNS glucosamine (N-acetyl)-6-sulfatase
GOLGA8B golgin A8 family, member B
IRF8 interferon regulatory factor 8
ISG20 interferon stimulated exonuclease gene 20kDa
KRT81 keratin 81, type II
LAMP3 lysosomal-associated membrane protein 3
LAMP5 lysosomal-associated membrane protein family, member 5
MALL mal, T-cell differentiation protein-like
MDFIC MyoD family inhibitor domain containing
NT5E 5'-nucleotidase, ecto (CD73)
OSBPL10 oxysterol binding protein-like 10
PCP4 Purkinje cell protein 4
PHYH phytanoyl-CoA 2-hydroxylase
PLN phospholamban
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRNP prion protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SERINC5 serine incorporator 5
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
SULF1 sulfatase 1
SVIL supervillin
SYNM synemin, intermediate filament protein
TFF3 trefoil factor 3 (intestinal)
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ARMCX3 armadillo repeat containing, X-linked 3
BAG3 BCL2-associated athanogene 3
CA12 carbonic anhydrase XII
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
FCGBP Fc fragment of IgG binding protein
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
HEBP1 heme binding protein 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HP haptoglobin
ITM2A integral membrane protein 2A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAPTM4B lysosomal protein transmembrane 4 beta
LYPLA1 lysophospholipase I
MUC16 mucin 16, cell surface associated
MYH10 myosin, heavy chain 10, non-muscle
PITX1 paired-like homeodomain 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
TCEAL4 transcription elongation factor A (SII)-like 4
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
ZNF395 zinc finger protein 395