BRD-K24656285_BL-079_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K24656285_BL-079_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BTG2 BTG family, member 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
COLEC12 collectin sub-family member 12
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNM1 dynamin 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FRZB frizzled-related protein
GPC3 glypican 3
H1FX H1 histone family, member X
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
JUP junction plakoglobin
KDM5D lysine (K)-specific demethylase 5D
LEF1 lymphoid enhancer-binding factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAB21L2 mab-21-like 2 (C. elegans)
MAN1A1 mannosidase, alpha, class 1A, member 1
MANSC1 MANSC domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
NLGN4X neuroligin 4, X-linked
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
REEP1 receptor accessory protein 1
RELN reelin
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SQRDL sulfide quinone reductase-like (yeast)
SYBU syntabulin (syntaxin-interacting)
TBXA2R thromboxane A2 receptor
TCEA2 transcription elongation factor A (SII), 2
TPBG trophoblast glycoprotein
WLS wntless Wnt ligand secretion mediator
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ALCAM activated leukocyte cell adhesion molecule
ANXA6 annexin A6
APOD apolipoprotein D
BAX BCL2-associated X protein
CALD1 caldesmon 1
CCDC85B coiled-coil domain containing 85B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COMP cartilage oligomeric matrix protein
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CTSZ cathepsin Z
CYR61 cysteine-rich, angiogenic inducer, 61
DCBLD2 discoidin, CUB and LCCL domain containing 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FERMT2 fermitin family member 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GADD45B growth arrest and DNA-damage-inducible, beta
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
ITGB5 integrin, beta 5
LGALS1 lectin, galactoside-binding, soluble, 1
LIF leukemia inhibitory factor
MMP10 matrix metallopeptidase 10
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NRIP1 nuclear receptor interacting protein 1
NUP85 nucleoporin 85kDa
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPAP2B phosphatidic acid phosphatase type 2B
PRMT1 protein arginine methyltransferase 1
RAD23B RAD23 homolog B (S. cerevisiae)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
TAGLN transgelin
TOP2A topoisomerase (DNA) II alpha 170kDa
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)