BRD-K24632213_7-Benzyl-8-isopropylsulfanyl-3-methyl-3,7-dihydro-purine-2,6-dione_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K24632213_7-Benzyl-8-isopropylsulfanyl-3-methyl-3,7-dihydro-purine-2,6-dione_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
FAM35A family with sequence similarity 35, member A
PNMA1 paraneoplastic Ma antigen 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TMX4 thioredoxin-related transmembrane protein 4
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1

decreased expression

Symbol Name
ANOS1 anosmin 1
ANPEP alanyl (membrane) aminopeptidase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHN1 chimerin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EXT1 exostosin glycosyltransferase 1
GPER1 G protein-coupled estrogen receptor 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
MAOA monoamine oxidase A
NEB nebulin
NVL nuclear VCP-like
PAM peptidylglycine alpha-amidating monooxygenase
PEA15 phosphoprotein enriched in astrocytes 15
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFTN1 raftlin, lipid raft linker 1
SEPT2 septin 2
SGK1 serum/glucocorticoid regulated kinase 1
STC1 stanniocalcin 1
WLS wntless Wnt ligand secretion mediator
XIST X inactive specific transcript (non-protein coding)