BRD-K24515980_QL-XI-92_MCF7_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K24515980_QL-XI-92_MCF7_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMDHD2 amidohydrolase domain containing 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ASPH aspartate beta-hydroxylase
ATXN1 ataxin 1
BHLHE40 basic helix-loop-helix family, member e40
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1ORF106 chromosome 1 open reading frame 106
CALD1 caldesmon 1
CD36 CD36 molecule (thrombospondin receptor)
CFD complement factor D (adipsin)
CHIC2 cysteine-rich hydrophobic domain 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DUSP5 dual specificity phosphatase 5
EIF5A eukaryotic translation initiation factor 5A
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GOLGA8A golgin A8 family, member A
HACD1 3-hydroxyacyl-CoA dehydratase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER1 homer scaffolding protein 1
HSPA1A heat shock 70kDa protein 1A
IFRD2 interferon-related developmental regulator 2
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
MAP1B microtubule-associated protein 1B
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MGLL monoglyceride lipase
MSN moesin
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDZK1IP1 PDZK1 interacting protein 1
PHYH phytanoyl-CoA 2-hydroxylase
PLAC8 placenta-specific 8
POU2AF1 POU class 2 associating factor 1
RAP2A RAP2A, member of RAS oncogene family
RBKS ribokinase
RRAGD Ras-related GTP binding D
SLC16A6 solute carrier family 16, member 6
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SRPX sushi-repeat containing protein, X-linked
STAP2 signal transducing adaptor family member 2
STK10 serine/threonine kinase 10
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TF transferrin
TM4SF1 transmembrane 4 L six family member 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNPO1 transportin 1
TNS3 tensin 3
TSKU tsukushi, small leucine rich proteoglycan
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BMP4 bone morphogenetic protein 4
C1ORF54 chromosome 1 open reading frame 54
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN3 cyclin-dependent kinase inhibitor 3
CSRP2 cysteine and glycine-rich protein 2
DCK deoxycytidine kinase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FASTKD5 FAST kinase domains 5
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GATA3 GATA binding protein 3
GHR growth hormone receptor
GLIPR1 GLI pathogenesis-related 1
GRWD1 glutamate-rich WD repeat containing 1
HEBP1 heme binding protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IPO13 importin 13
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
MACF1 microtubule-actin crosslinking factor 1
MECOM MDS1 and EVI1 complex locus
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
NPY neuropeptide Y
PAN2 PAN2 poly(A) specific ribonuclease subunit
POSTN periostin, osteoblast specific factor
RAD51C RAD51 paralog C
RAI14 retinoic acid induced 14
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
WFDC2 WAP four-disulfide core domain 2
ZNF395 zinc finger protein 395