BRD-K24515980_QL-XI-92_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

84 genes differentially expressed following the BRD-K24515980_QL-XI-92_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COTL1 coactosin-like F-actin binding protein 1
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
E2F2 E2F transcription factor 2
ETNPPL ethanolamine-phosphate phospho-lyase
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GHR growth hormone receptor
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB10 growth factor receptor-bound protein 10
HSPB8 heat shock 22kDa protein 8
IL13RA2 interleukin 13 receptor, alpha 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KLF4 Kruppel-like factor 4 (gut)
KLK6 kallikrein-related peptidase 6
LAMC2 laminin, gamma 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP7 microtubule-associated protein 7
MCUR1 mitochondrial calcium uniporter regulator 1
MIR22HG MIR22 host gene
MMP12 matrix metallopeptidase 12
MYH11 myosin, heavy chain 11, smooth muscle
NNMT nicotinamide N-methyltransferase
NPAS2 neuronal PAS domain protein 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PALLD palladin, cytoskeletal associated protein
PERP PERP, TP53 apoptosis effector
PHLDA1 pleckstrin homology-like domain, family A, member 1
SIK1 salt-inducible kinase 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPON1 spondin 1, extracellular matrix protein
SPP1 secreted phosphoprotein 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNJ2 synaptojanin 2
SYNM synemin, intermediate filament protein
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
TPD52 tumor protein D52
TSPAN8 tetraspanin 8
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
CCND2 cyclin D2
CFB complement factor B
CXCL10 chemokine (C-X-C motif) ligand 10
ERAP2 endoplasmic reticulum aminopeptidase 2
FGG fibrinogen gamma chain
FLRT3 fibronectin leucine rich transmembrane protein 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GTSE1 G-2 and S-phase expressed 1
HIST1H4C histone cluster 1, H4c
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT15 keratin 15, type I
KRT5 keratin 5, type II
LTF lactotransferrin
LYZ lysozyme
MATN2 matrilin 2
MSMB microseminoprotein, beta-
NCAM1 neural cell adhesion molecule 1
NES nestin
NMU neuromedin U
OLFM4 olfactomedin 4
PEG10 paternally expressed 10
PFN2 profilin 2
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
RPS5 ribosomal protein S5
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SOX11 SRY (sex determining region Y)-box 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCF4 transcription factor 4
TIMP1 TIMP metallopeptidase inhibitor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
WDR7 WD repeat domain 7