BRD-K24496482_SB590885_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K24496482_SB590885_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
APOE apolipoprotein E
CLDN3 claudin 3
DEPTOR DEP domain containing MTOR-interacting protein
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
GUSBP11 glucuronidase, beta pseudogene 11
GUSBP3 glucuronidase, beta pseudogene 3
HBB hemoglobin, beta
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
LDHB lactate dehydrogenase B
LYN LYN proto-oncogene, Src family tyrosine kinase
MSX1 msh homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RHOB ras homolog family member B
RRAGD Ras-related GTP binding D
SCGB2A1 secretoglobin, family 2A, member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STS steroid sulfatase (microsomal), isozyme S
STX1A syntaxin 1A (brain)
TKT transketolase
TNC tenascin C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WDR61 WD repeat domain 61
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADRB2 adrenoceptor beta 2, surface
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BCHE butyrylcholinesterase
CADM1 cell adhesion molecule 1
CD59 CD59 molecule, complement regulatory protein
CD9 CD9 molecule
CREB1 cAMP responsive element binding protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DICER1 dicer 1, ribonuclease type III
DMD dystrophin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
HOPX HOP homeobox
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KDM5D lysine (K)-specific demethylase 5D
KIF5C kinesin family member 5C
KRT23 keratin 23, type I
LMO4 LIM domain only 4
MN1 meningioma (disrupted in balanced translocation) 1
NRIP1 nuclear receptor interacting protein 1
PBX1 pre-B-cell leukemia homeobox 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCH protein kinase C, eta
RNF167 ring finger protein 167
RPS4Y1 ribosomal protein S4, Y-linked 1
RSBN1 round spermatid basic protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SIRT3 sirtuin 3
SLIT2 slit homolog 2 (Drosophila)
SNX7 sorting nexin 7
SPP1 secreted phosphoprotein 1
STC2 stanniocalcin 2
TNS3 tensin 3