BRD-K24496482_SB590885_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K24496482_SB590885_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CHL1 cell adhesion molecule L1-like
COL4A5 collagen, type IV, alpha 5
CXCL8 chemokine (C-X-C motif) ligand 8
DLK1 delta-like 1 homolog (Drosophila)
EGR1 early growth response 1
EGR3 early growth response 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCGBP Fc fragment of IgG binding protein
GREB1 growth regulation by estrogen in breast cancer 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
IER3 immediate early response 3
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
MCL1 myeloid cell leukemia 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAV3 neuron navigator 3
PIP prolactin-induced protein
PNMAL1 paraneoplastic Ma antigen family-like 1
PSPH phosphoserine phosphatase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNASET2 ribonuclease T2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
STEAP1 six transmembrane epithelial antigen of the prostate 1
TRIL TLR4 interactor with leucine-rich repeats
ZIC1 Zic family member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL11A1 collagen, type XI, alpha 1
DACH1 dachshund family transcription factor 1
DNM1L dynamin 1-like
ECM1 extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
JCHAIN joining chain of multimeric IgA and IgM
MMP9 matrix metallopeptidase 9
PGAM1 phosphoglycerate mutase 1 (brain)
PKM pyruvate kinase, muscle
PLIN2 perilipin 2
SMAD7 SMAD family member 7
SPP1 secreted phosphoprotein 1
TNS3 tensin 3
VCAM1 vascular cell adhesion molecule 1