BRD-K23922020_Arecaidine propargyl ester tosylate_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K23922020_Arecaidine propargyl ester tosylate_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGAP29 Rho GTPase activating protein 29
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
COG7 component of oligomeric golgi complex 7
COL4A5 collagen, type IV, alpha 5
CTNND1 catenin (cadherin-associated protein), delta 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DEPTOR DEP domain containing MTOR-interacting protein
EIF5A eukaryotic translation initiation factor 5A
EXT1 exostosin glycosyltransferase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
HBB hemoglobin, beta
IFNAR1 interferon (alpha, beta and omega) receptor 1
IPO13 importin 13
ISOC1 isochorismatase domain containing 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LDOC1 leucine zipper, down-regulated in cancer 1
LOC100505650 uncharacterized LOC100505650
NELL2 NEL-like 2 (chicken)
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE6 ribonuclease, RNase A family, k6
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOX11 SRY (sex determining region Y)-box 11
SRPX sushi-repeat containing protein, X-linked
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
ZNF274 zinc finger protein 274
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADCY3 adenylate cyclase 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BGN biglycan
BST2 bone marrow stromal cell antigen 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFH complement factor H
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DCXR dicarbonyl/L-xylulose reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
EPHA3 EPH receptor A3
F3 coagulation factor III (thromboplastin, tissue factor)
FA2H fatty acid 2-hydroxylase
G0S2 G0/G1 switch 2
GMDS GDP-mannose 4,6-dehydratase
GPX2 glutathione peroxidase 2
GRWD1 glutamate-rich WD repeat containing 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IL1R2 interleukin 1 receptor, type II
INHBA inhibin, beta A
KLF6 Kruppel-like factor 6
KRT17 keratin 17, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMCD1 LIM and cysteine-rich domains 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LPL lipoprotein lipase
MCUR1 mitochondrial calcium uniporter regulator 1
NEFL neurofilament, light polypeptide
NFIB nuclear factor I/B
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFC2 replication factor C (activator 1) 2, 40kDa
RPA3 replication protein A3, 14kDa
RPS11 ribosomal protein S11
RRAGD Ras-related GTP binding D
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFN stratifin
SIK1 salt-inducible kinase 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNX7 sorting nexin 7
SPINK1 serine peptidase inhibitor, Kazal type 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TBX2 T-box 2
THY1 Thy-1 cell surface antigen
TMEM47 transmembrane protein 47
TSPAN8 tetraspanin 8
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)