BRD-K23875128_Rho kinase inhibitor III [rockout]_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

81 genes differentially expressed following the BRD-K23875128_Rho kinase inhibitor III [rockout]_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ANOS1 anosmin 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP1 aquaporin 1 (Colton blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CA2 carbonic anhydrase II
COL10A1 collagen, type X, alpha 1
CPM carboxypeptidase M
DDIT4 DNA-damage-inducible transcript 4
FABP4 fatty acid binding protein 4, adipocyte
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LIMCH1 LIM and calponin homology domains 1
METTL7A methyltransferase like 7A
PLA2G16 phospholipase A2, group XVI
PLIN1 perilipin 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBP4 retinol binding protein 4, plasma
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC38A2 solute carrier family 38, member 2
SPON1 spondin 1, extracellular matrix protein
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ANPEP alanyl (membrane) aminopeptidase
ATF3 activating transcription factor 3
C8ORF4 chromosome 8 open reading frame 4
CBR3 carbonyl reductase 3
CCL20 chemokine (C-C motif) ligand 20
CFLAR CASP8 and FADD-like apoptosis regulator
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DES desmin
EMP3 epithelial membrane protein 3
ERBB2IP erbb2 interacting protein
FZD7 frizzled class receptor 7
GDF15 growth differentiation factor 15
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLHL41 kelch-like family member 41
KRT5 keratin 5, type II
MAP2K3 mitogen-activated protein kinase kinase 3
MARCKSL1 MARCKS-like 1
MX1 MX dynamin-like GTPase 1
MYBPC1 myosin binding protein C, slow type
MYOT myotilin
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PRAME preferentially expressed antigen in melanoma
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A7 S100 calcium binding protein A7
SACS sacsin molecular chaperone
SLN sarcolipin
SYNM synemin, intermediate filament protein
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUBB2A tubulin, beta 2A class IIa
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2S ubiquitin-conjugating enzyme E2S
YBX3 Y box binding protein 3
ZBTB20 zinc finger and BTB domain containing 20