BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CADM1 cell adhesion molecule 1
CFD complement factor D (adipsin)
CPD carboxypeptidase D
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPAS1 endothelial PAS domain protein 1
G6PD glucose-6-phosphate dehydrogenase
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
LCN2 lipocalin 2
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NEBL nebulette
NPTX2 neuronal pentraxin II
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PGD phosphogluconate dehydrogenase
PPARG peroxisome proliferator-activated receptor gamma
RAP1GAP RAP1 GTPase activating protein
RGCC regulator of cell cycle
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
STK10 serine/threonine kinase 10
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VSNL1 visinin-like 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIRC5 baculoviral IAP repeat containing 5
CA12 carbonic anhydrase XII
CDK1 cyclin-dependent kinase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DEGS1 delta(4)-desaturase, sphingolipid 1
ESR1 estrogen receptor 1
FXYD3 FXYD domain containing ion transport regulator 3
IGHM immunoglobulin heavy constant mu
IQCG IQ motif containing G
KIF20A kinesin family member 20A
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY1R neuropeptide Y receptor Y1
SEPW1 selenoprotein W, 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TFF1 trefoil factor 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBA1A tubulin, alpha 1a
UBE2A ubiquitin-conjugating enzyme E2A