BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
ANXA10 annexin A10
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACE2 beta-site APP-cleaving enzyme 2
CAV2 caveolin 2
CD163 CD163 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EMP1 epithelial membrane protein 1
FABP4 fatty acid binding protein 4, adipocyte
FHL2 four and a half LIM domains 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
IL1R2 interleukin 1 receptor, type II
INPP1 inositol polyphosphate-1-phosphatase
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF4 Kruppel-like factor 4 (gut)
KLK10 kallikrein-related peptidase 10
KRT19 keratin 19, type I
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LPL lipoprotein lipase
MBNL2 muscleblind-like splicing regulator 2
MIR22HG MIR22 host gene
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
ODC1 ornithine decarboxylase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
RBP4 retinol binding protein 4, plasma
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SDC4 syndecan 4
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TES testin LIM domain protein
THBD thrombomodulin
TXNRD1 thioredoxin reductase 1
UPP1 uridine phosphorylase 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CA12 carbonic anhydrase XII
CCNB2 cyclin B2
CCND2 cyclin D2
CCNF cyclin F
COL3A1 collagen, type III, alpha 1
HIST1H2BG histone cluster 1, H2bg
HOPX HOP homeobox
KIAA0101 KIAA0101
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAOA monoamine oxidase A
NEFH neurofilament, heavy polypeptide
NPY neuropeptide Y
PCNA proliferating cell nuclear antigen
RGS2 regulator of G-protein signaling 2
TYMS thymidylate synthetase